PreLONG FAQ

1. How many do I take per day?   
   • The recommended dose is one pill per day. It is safe to take up to 3 pills per day
     
     
2. How long does it take to work?
   • You should notice a difference after taking PreLONG for 1-2 weeks
     
     
3. What will I notice?
   • You should notice that you can increase the time to ejaculation by 1-3 minutes.
   • You may also notice a positive impact on mood
   • Many people taking St John’s Wort sleep more soundly
     
     
4. How does St John’s Wort work to increase time to ejaculation?
   • St John’s Wort is a natural selective serotonin reuptake inhibitor. Serotonin is an important factor in ejaculation and by increasing serotonin, you can increase the time until climax. 
     
     
5. Can I just take regular St. John’s Wort?
   • PreLONG contains a particular extract of Hypericum that is a natural selective serotonin reuptake inhibitor. Regular St. John’s Wort would contain Hyperacin which can have side effects like sedation, GI disturbance and sexual dysfunction. 
     
     
6. What is L-Citrulline?
   • L-Citrulline is extracted from fermented Watermelon Rind. It is converted by the kidney into L-Arginine which is a potent Nitric Oxide Booster.  Nitric Oxide is the signaling molecule your body uses to dilate arteries and promote circulation. 
     
     
7. What else is St. John’s Wort used for?
   • John’s Wort is used to promote a healthy mood.
   • It is also used to improve sleep at night, decrease rheumatic pain including gout, improve seasonal effective disorder.
     
     
8. What are the side effects of St. John’s Wort?
   • Side effects are usually mild and include stomach upset, fatigue, headache, dry mouth, dizziness, and skin rash. It can also increase skin sensitivity to light.
     
     
9. Can you take PreLONG with other medications?
   • St John’s Wort is known to interact with the cytochrome p-450 system, the body’s primary site of drug break-down. By increasing the activity of the CYP 450 system, St John’s Wort can result in increased or decreased breakdown of other drugs, changing their effectiveness.  The dose of St John’s Wort in PreLONG is relatively low and the risk of interaction is relatively small. 

Adverse effects of St. John’s Wort

Adverse effects of St. John’s Wort are also well-studied.  Side effects, when they occur, are generally mild and include stomach upset, tiredness, headache, dry mouth, dizziness, and skin rash.  It can also increase skin sensitivity to light (photosensitivity).

St. John’s Wort is also known to interact with the cytochrome p-450 (CYP450) system, the body’s primary site of drug break-down.  By increasing the activity of the CYP450, St. John’s Wort can result in increased breakdown of other drugs, decreasing their effectiveness.  This means the herb can result in significant interactions; some of the specific medications St. John’s Wort interacts with include: